Embedded into the test strip are antibodies that bind to a COVID-19 specific biomarker, the immunoglobulin specific to the viral spike (s) protein.

When a sample (blood, serum or plasma) is added to one end of the test, it flows along the test strip and interacts with these antibodies. If the test subject has had COVID-19 or a vaccine, the biomarkers in their blood will bind to the antibodies on in the test cassette and can be read by the AFS-1000 analyser.